| Rank | City | Population |
| 1 | Detroit | 672,351 |
| 2 | Grand Rapids city | 199,417 |
| 3 | Warren city | 134,188 |
| 4 | Sterling Heights | 132,296 |
| 5 | Ann Arbor city | 121,093 |
| 6 | Lansing city | 117,488 |
| 7 | Clinton charter township | 100,328 |
| 8 | Flint city | 95,999 |
| 9 | Dearborn | 94,328 |
| 10 | Livonia | 93,970 |
| 11 | Canton | 92,829 |
| 12 | Macomb | 90,233 |
| 13 | Troy city | 84,051 |
| 14 | Westland | 81,713 |
| 15 | Farmington Hills | 80,937 |
| 16 | Shelby charter township | 79,840 |
| 17 | Kalamazoo city | 76,106 |
| 18 | Wyoming | 75,999 |
| 19 | Rochester Hills | 74,340 |
| 20 | Southfield city | 72,966 |
| 21 | Waterford | 72,842 |
| 22 | West Bloomfield | 65,850 |
| 23 | Taylor | 61,164 |
| 24 | Novi city | 60,439 |
| 25 | Pontiac | 59,714 |
| 26 | Royal Oak city | 59,256 |
| 27 | St. Clair Shores | 59,184 |
| 28 | Dearborn Heights | 55,630 |
| 29 | Ypsilanti | 55,116 |
| 30 | Georgetown | 52,155 |
| 31 | Kentwood | 51,780 |
| 32 | Battle Creek | 51,084 |
| 33 | Portage city | 49,224 |
| 34 | East Lansing | 48,437 |
| 35 | Saginaw city | 48,407 |
| 36 | Roseville | 47,160 |
| 37 | Redford | 46,811 |
| 38 | Chesterfield | 46,010 |
| 39 | Commerce | 43,701 |
| 40 | Meridian | 42,853 |
| 41 | Bloomfield charter township | 42,031 |
| 42 | Midland city | 41,922 |
| 43 | Orion | 39,361 |
| 44 | Saginaw | 39,251 |
| 45 | Pittsfield | 38,800 |
| 46 | Holland charter township | 38,312 |
| 47 | Muskegon city | 37,317 |
| 48 | Independence | 36,882 |
| 49 | Grand Blanc | 36,677 |
| 50 | Lincoln Park | 36,525 |
| 51 | Plainfield charter township | 33,920 |
| 52 | Holland city | 33,329 |
| 53 | Delta | 33,203 |
| 54 | Bay City | 32,892 |
| 55 | Jackson | 32,251 |
| 56 | Eastpointe | 32,221 |
| 57 | Brownstown | 31,862 |
| 58 | Bedford township | 31,667 |
| 59 | White Lake | 31,327 |
| 60 | Flint | 30,461 |
| 61 | Madison Heights | 30,000 |
| 62 | Oak Park | 29,446 |
| 63 | Northville | 29,174 |
| 64 | Southgate | 29,129 |
| 65 | Port Huron city | 28,918 |
| 66 | Burton | 28,598 |
| 67 | Van Buren | 28,376 |
| 68 | Washington charter township | 28,180 |
| 69 | Delhi | 27,817 |
| 70 | Gaines charter township | 27,093 |
| 71 | Allen Park | 27,089 |
| 72 | Plymouth | 27,060 |
| 73 | Garden City | 26,565 |
| 74 | Allendale | 26,287 |
| 75 | Mount Pleasant | 25,290 |
| 76 | Wyandotte | 24,944 |
| 77 | Harrison | 24,934 |
| 78 | Walker city | 24,930 |
| 79 | Norton Shores | 24,557 |
| 80 | Inkster | 24,398 |
| 81 | Byron | 24,339 |
| 82 | Auburn Hills | 23,984 |
| 83 | Blackman | 23,580 |
| 84 | Romulus | 23,544 |
| 85 | Oshtemo | 23,118 |
| 86 | Kalamazoo | 22,663 |
| 87 | Oxford | 22,558 |
| 88 | Summit township | 22,437 |
| 89 | Hamburg | 21,728 |
| 90 | Hamtramck | 21,704 |
| 91 | Birmingham | 21,272 |
| 92 | Ypsilanti city | 20,792 |
| 93 | Marquette city | 20,631 |
| 94 | Adrian city | 20,550 |
| 95 | Genesee | 20,506 |
| 96 | Genoa | 20,470 |
| 97 | Mount Morris | 20,406 |
| 98 | Lyon charter township | 20,373 |
| 99 | Ferndale | 20,139 |
| 100 | Highland charter township | 20,081 |